Osamudiamen Ebohon

August 2022 – present, Graduate Research Assistant, Biochemistry, Virginia Tech

October 2021 – March 2022, Laboratory worker, NHS Integrated Covid Hub, North East, Lighthouse Laboratory, UK

April 2018 – September 2021, Assistant Lecturer, Micheal and Cecilia Ibru University, Nigeria

October 2016 – March 2018, Research scientist, Metro Research Laboratory and Biotechnology, Nigeria

Travel award: Bioinformatics and molecular biology hands-on training on pathogens and cancer research, 2019

Best research scientist: Metro Research and Biotechnology Africa Ltd, 2017

My research is focused on developing an effective tool for diagnosing Lyme disease. Current methods of diagnosing Lyme disease are not effective - they lack specificity and sensitivity. It can take up to 4 weeks to raise antibodies that can be used for the diagnosis and the antibodies raised can be persistent even after clearance of the causative agent, Borrelia burgdorferi. My project involves the use of muropeptides released by B. burgdorferi as an antigen to develop a novel specific and sensitive method for Lyme disease diagnosis.

During the Covid-19 pandemic, I worked with the NHS Integrated Covid Hub, Lighthouse Laboratory, UK. This enabled me to contribute to controlling the pandemic by carrying out numerous tests on thousands of samples from COVID-19 patients. 

Ebohon, O. Hart, B.A. and Jutras, B.L. (2023) Vertebrate–arthropod communication dictates tick development and pathogen transmission. Trends in Parasitology. 39(5): 235-327. https://doi.org/10.1016/j.pt.2023.03.010

Ebohon, O., Irabor, F., Erhunse, N., Omagene, A. and Omoregie, E.S. (2021). In vitro antiplasmodial activity, cytotoxicity and gas chromatography – flame ionization detector metabolites fingerprint of extracts and fractions from Tetrorchidium didymostemon. Journal of Ayurveda and Integrative Medicine. 12: 480-488. https://doi.org/10.1016/j.jaim.2021.05.004

Ebohon, O., Irabor, F. and Omoregie, E.S. (2021). Ascorbic acid coadministration with artesunate-amodiaquine, up-regulated antioxidant enzymes gene expression in bone marrow cells and elicited biochemical changes in Plasmodium berghei-infected mice. SN Applied Sciences. 3(6): 1-11. https://doi.org/10.1007/s42452-020-04063-5

Irabor, F., Ebohon, O., Ibukun, O., Ayevbuomwan, M.E. and Omoregie, E.S. (2021). Biological activity and subchronic toxicity study of Allanblackia floribunda Oliv. on experimental rats. Scientific African. https://doi.org/10.1016/j.sciaf.2021.e00950

Ebohon, O., Obienu, A.C., Irabor, F., Amadin, F.I. and Omoregie, E.S. (2021). Evaluating the impact of COVID-19 pandemic lockdown on education in Nigeria: Insights from teachers and students on virtual/online learning. Bulletin of the National Research Centre. 45(1): 1-11. https://doi.org/10.1186/s42269-021-00538-6

Eze, D.M., Duru, V., Ebohon, O. and Adigun, T.O. (2021). A bioinformatics analysis and homology modeling of polyadenylate binding protein of Plasmodium falciparum 3D7. Journal of Computational Biology and Bioinformatics Research. 11(1): 1-9. https://doi.org/10.5897/JCBBR2020.0127

Ebohon, O., Irabor, F., Ebohon, L.O. and Omoregie, E.S. (2019). Therapeutic failure after regimen with artemether-lumefantrine combination therapy: a report of three cases in Benin City, Nigeria. Revista da Sociedade Brasileira de Medicina Tropical. 52: e20190163. PMID: 31618306, https://dx.doi.org/10.1590/0037-8682-0163-2019

Oral Presentations

Ebohon, O., Irabor, F. and Omoregie, E.S. (2021). Ascorbic acid coadministration with artesunate-amodiaquine, up-regulated antioxidant enzymes gene expression in bone marrow cells and elicited biochemical changes in Plasmodium berghei-infected mice. EMBL conference: BioMalPar XVII: Biology and Pathology of the Malaria Parasite. May 25 – 27th, 2021.

Omoregie, E.S., Ebohon, O., Obuseh, F.A., Erhunse, N. and Irabor, F. (2016). 28 days oral toxicity study of atovaquone-proguanil antimalarial combination drug in male wistar rats. 2nd University of Benin Annual Research Day (UBARD) Conference. 20th – 21st October, 2016.